Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441817 | 0.93 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7438143 | 0.85 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5599676 | 0.81 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL7434787 | 0.75 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL7429882 | 0.74 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL5600453 | 0.74 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5599675 | 0.72 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5599679 | 0.71 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL5600192 | 0.69 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL16606731 | 0.67 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |