SCHEMBL7441828

SCHEMBL7441828

CC(=O)Nc1ccc(S(N)(=O)=O)c(NC(C)=O)c1N

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CA1 P00915 10/20 0.49
CA2 P00918 10/20 0.49
CA9 Q16790 8/20 0.49
CA12 O43570 2/20 0.44
NPC1 O15118 2/20 0.42
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
PIK3C3 Q8NEB9 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
CA7 P43166 1/20 0.38
PKM P14618 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3816056 0.79 CA1 (0.56) ALDH1A1CA1CA2CA9CA12
SCHEMBL7570371 0.77 ALDH1A1 (0.64) ALDH1A1CA1CA2CA9CA12
SCHEMBL11358245 0.75 CA1 (0.53) ALDH1A1CA1CA2CA9CA12
SCHEMBL8779843 0.74 NPC1 (0.42) ALDH1A1CA1CA2CA9CA12
SCHEMBL4463532 0.73 CA1 (0.70) ALDH1A1CA1CA2CA9CA12
SCHEMBL31309573 0.73 CA1 (0.70) ALDH1A1CA1CA2CA9CA12
SCHEMBL27575211 0.72 CA1 (0.54) ALDH1A1CA1CA2CA9CA12
SCHEMBL20441085 0.71 CA2 (0.46) ALDH1A1CA1CA2CA9CA12
SCHEMBL11383168 0.71 CA1 (0.51) ALDH1A1CA1CA2CA9CA12
SCHEMBL10797625 0.70 CA1 (0.47) ALDH1A1CA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002062769-A2 PREPARATION AND PURIFICATION OF ANTIVIRAL DISULFONIC ACID DISODIUM SALT WYETH (US) 2002-08-15 WO disclosed