SCHEMBL7441996

SCHEMBL7441996

C=C(Cc1ccccc1C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.59
SHBG P04278 1/20 0.47
HPGD P15428 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.42
GAA P10253 1/20 0.42
PTGS2 P35354 1/20 0.42
NPC1 O15118 2/20 0.42
KDM4E B2RXH2 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CASP3 P42574 1/20 0.41
CASP7 P55210 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746636 0.86 AKR1B1 (0.46) CTBP2HPGDALDH1A1KMT2AMEN1
SCHEMBL11389910 0.85 CTBP2 (0.44) CTBP2HPGDALDH1A1KMT2AMEN1
SCHEMBL29153131 0.84 ALDH1A1 (0.46) CTBP2SHBGHPGDALDH1A1KMT2A
SCHEMBL7336703 0.82 AKR1B1 (0.41) CTBP2SHBGALDH1A1MAPTPTGS2
SCHEMBL1920462 0.81 CTBP2 (0.47) CTBP2HPGDALDH1A1KMT2AMAPT
SCHEMBL9310058 0.81 ALDH1A1 (0.42) CTBP2ALDH1A1KMT2AMEN1NPC1
SCHEMBL11467086 0.80 AKR1B1 (0.42) CTBP2ALDH1A1KMT2AMEN1MAPT
SCHEMBL2935163 0.80 CTBP2 (0.62) CTBP2SHBGHPGDALDH1A1KMT2A
SCHEMBL2528595 0.79 AKR1B1 (0.61) CTBP2SHBGHPGDALDH1A1KMT2A
SCHEMBL29631318 0.79 AKR1B1 (0.61) CTBP2SHBGHPGDALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110885414-A ATRP method ester-based amide block polymer modified polycarboxylic acid water reducing agent and preparation method thereof 湖北工业大学 2020-03-17 CN claimed
US-5821306-A POLYMER BLEND CONSISTING OF POLYPHENYLETHYL METHACRYLATE AND POLYPHENYLETHYL ACRYLATE PHARMACIA & UPJOHN GRONINGEN BV (NL) 1998-10-13 US claimed
EP-0784652-A1 INTRAOCULAR LENS MATERIALS Pharmacia & Upjohn Aktiebolag (SE) 1997-07-23 EP claimed
WO-1996011235-A1 INTRAOCULAR LENS MATERIALS PHARMACIA & UPJOHN AB (SE) 1996-04-18 WO claimed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed
CN-110885414-A ATRP method ester-based amide block polymer modified polycarboxylic acid water reducing agent and preparation method thereof 湖北工业大学 2020-03-17 CN disclosed
CN-102653495-B Drought resisting fertilizer specially used for corn and preparation method thereof MAANSHAN KEBANG ECOLOGY CO LTD 2014-07-09 CN disclosed
CN-102653499-B Drought resisting insecticide fertilizer specially used for corn and preparation method thereof MAANSHAN KEBANG ECO FERTILIZER 2014-05-21 CN disclosed
CN-102653495-A Drought resisting fertilizer specially used for corn and preparation method thereof MAANSHAN KEBANG ECOLOGY CO LTD 2012-09-05 CN disclosed
CN-102653499-A Drought resisting insecticide fertilizer specially used for corn and preparation method thereof MAANSHAN KEBANG ECOLOGY CO LTD 2012-09-05 CN disclosed
US-5821306-A POLYMER BLEND CONSISTING OF POLYPHENYLETHYL METHACRYLATE AND POLYPHENYLETHYL ACRYLATE PHARMACIA & UPJOHN GRONINGEN BV (NL) 1998-10-13 US disclosed
US-5691094-A LITHOGRAPHY, INPROVED TRANSFERABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-11-25 US disclosed
EP-0784652-A1 INTRAOCULAR LENS MATERIALS Pharmacia & Upjohn Aktiebolag (SE) 1997-07-23 EP disclosed
US-5648191-A Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1997-07-15 US disclosed
US-5597672-A Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1997-01-28 US disclosed
WO-1996011235-A1 INTRAOCULAR LENS MATERIALS PHARMACIA & UPJOHN AB (SE) 1996-04-18 WO disclosed
US-5501929-A TONER IMAGES ON TRANSFER LAYER OF THERMOPLASTIC RESIN FORLIGHT SENSITIVE ELEMENT FUJI PHOTO FILM CO., LTD. (JP) 1996-03-26 US disclosed
US-4929641-A DIURETICS, ANGIOTENSIN CONVERTING ENZYMES SCHERING CORPORATION (US) 1990-05-29 US disclosed
US-4329495-A USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES PFIZER INC. (US) 1982-05-11 US disclosed