Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727292 | 0.80 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1714208 | 0.80 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL13551145 | 0.80 | DGAT1 (0.33) | DGAT1 | |
| Hydrochloric Acid SCHEMBL28000852 | 0.78 | DGAT1 (0.48) | DGAT1 | |
| Ammonia Solution, Strong SCHEMBL5360181 | 0.77 | CTSK (0.32) | — | |
| SCHEMBL3416095 | 0.76 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL19558503 | 0.76 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL14839078 | 0.76 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL783662 | 0.74 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL11035432 | 0.74 | DGAT1 (0.30) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001261-A | Process for the production of 1-[(dimethylamino)methyl]-6-phenyl-4H-imidazo[1,2-a][1,4]-benzodiazepine | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001262-A | Process for the production of 1-[(dimethylamino)methyl]-6-phenyl-4H-triazolo[4,3-a][1,4]-benzodiazepine | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |