Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 10/20 | 0.38 |
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350013 | 0.77 | DGAT1 (0.46) | DGAT1CTSK | |
| SCHEMBL17617203 | 0.77 | DGAT1 (0.46) | DGAT1CTSK | |
| SCHEMBL248088 | 0.77 | DGAT1 (0.37) | DGAT1CTSSCTSKMEN1KMT2A | |
| SCHEMBL9911580 | 0.75 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL19648659 | 0.75 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL8161656 | 0.75 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL12168855 | 0.75 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL18492898 | 0.75 | CYP3A4 (0.42) | MEN1KMT2ADPP4 | |
| SCHEMBL28455914 | 0.75 | CYP3A4 (0.42) | MEN1KMT2ADPP4 | |
| SCHEMBL21436393 | 0.73 | DGAT1 (0.43) | DGAT1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |