SCHEMBL9911580

SCHEMBL9911580

COC(=O)C(C)(CC(C)C)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.45
MMP8 P22894 1/20 0.42
CA7 P43166 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PIK3CD O00329 1/20 0.31
AR P10275 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10243710 0.83 DGAT1 (0.45) DGAT1MMP8CA7CA1CA2
SCHEMBL26417982 0.82 MMP8 (0.39) DGAT1MMP8
SCHEMBL10098425 0.82 MMP8 (0.42) DGAT1MMP8CA1CA2
SCHEMBL13447889 0.81 MMP8 (0.37) DGAT1MMP8
SCHEMBL15935717 0.81 MMP8 (0.37) DGAT1MMP8
SCHEMBL18560733 0.81 MMP8 (0.41) DGAT1MMP8
SCHEMBL15203352 0.81 MMP8 (0.37) DGAT1MMP8
SCHEMBL13389934 0.80 MMP8 (0.41) DGAT1MMP8CA1CA2
SCHEMBL13350013 0.80 DGAT1 (0.46) DGAT1MMP8CA7CA1CA2
SCHEMBL17617203 0.80 DGAT1 (0.46) DGAT1MMP8CA7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669368-A High-purity low-chroma gemfibrozil preparation method 浙江精进药业有限公司 2016-06-15 CN claimed
US-20230148217-A1 FILM INSERT MOLDED ARTICLE AND MANUFACTURING METHOD FOR FILM INSERT MOLDED ARTICLE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-05-11 US disclosed
EP-2799913-B1 OPTICAL MEMBER SET AND SOLID-STATE IMAGE SENSOR USING SAME FUJIFILM CORP (JP) 2017-02-01 EP disclosed
CN-105669368-A High-purity low-chroma gemfibrozil preparation method 浙江精进药业有限公司 2016-06-15 CN disclosed
EP-2799913-A1 OPTICAL MEMBER SET AND SOLID-STATE IMAGE SENSOR USING SAME FUJI-FILM Corporation (JP) 2014-11-05 EP disclosed
US-8574433-B2 Ion exchange porous resins for solid phase extraction and chromatography WATERS TECHNOLOGIES CORPORATION (US) 2013-11-05 US disclosed
US-8197692-B2 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof WATERS TECHNOLOGIES CORPORATION (US) 2012-06-12 US disclosed
US-20100324159-A1 NOVEL ION EXCHANGE POROUS RESINS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2010-12-23 US disclosed
WO-2010140483-A1 FLUORINE-CONTAINING COMPOUND, FLUORINE-CONTAINING POLYMER COMPOUND, RESIST COMPOSITION, TOP COAT COMPOSITION AND PATTERN FORMATION METHOD セントラル硝子株式会社 (JP) 2010-12-09 WO disclosed
US-20100300972-A1 POROUS MATERIALS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF WATERS TECHNOLOGIES CORPORATION (US) 2010-12-02 US disclosed
US-7731844-B2 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof WATERS TECHNOLOGIES CORPORATION (US) 2010-06-08 US disclosed
US-7442299-B2 Ion exchange porous resins for solid phase extraction and chromatography WATERS INVESTMENTS LIMITED (US) 2008-10-28 US disclosed
US-20070205156-A1 Novel ion exchange porous resins for solid phase extraction and chromatography WATERS INVESTMENTS LIMITED (US) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324159-A1 NOVEL ION EXCHANGE POROUS RESINS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY SLC9A2, SLC9A1, SLC9A3 DGAT1 3154/4885MMP8 1395/4885CA7 1525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.