Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 6/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324204 | 1.00 | SLC7A5 (0.41) | SLC7A5PTPN1NPY4RNPY1RNPY2R | |
| SCHEMBL7324200 | 1.00 | SLC7A5 (0.41) | SLC7A5PTPN1NPY4RNPY1RNPY2R | |
| SCHEMBL7313525 | 0.91 | SLC7A5 (0.48) | SLC7A5ERAP2ERAP1LNPEPLARS1 | |
| SCHEMBL7313531 | 0.91 | SLC7A5 (0.48) | SLC7A5ERAP2ERAP1LNPEPLARS1 | |
| SCHEMBL30799510 | 0.90 | SLC7A5 (0.44) | SLC7A5PTPN1NPY4RNPY1RNPY2R | |
| SCHEMBL30799781 | 0.88 | DPP4 (0.39) | NPY4RNPY1RNPY2RNPY5RMMP2 | |
| SCHEMBL3303877 | 0.87 | SLC7A5 (0.50) | SLC7A5MMP2CTSDBACE1LARS1 | |
| SCHEMBL3303883 | 0.87 | SLC7A5 (0.50) | SLC7A5MMP2CTSDBACE1LARS1 | |
| SCHEMBL10363301 | 0.86 | SLC7A5 (0.47) | SLC7A5PTPN1NPY4RNPY1RNPY2R | |
| SCHEMBL10363299 | 0.86 | SLC7A5 (0.47) | SLC7A5PTPN1NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4771037-A | N-CARBOXYALKYL-PEPTIDES USEFUL AS INHIBITORS OF PROTEOGLYCANASE | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |