Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779517 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL3399492 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL23956955 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL18780918 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL1177836 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1NOTUMLMNA | |
| SCHEMBL7383260 | 0.75 | DDB1 (0.55) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL395429 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| Cyclopropane SCHEMBL29003079 | 0.74 | ALDH1A1 (0.69) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| SCHEMBL15777771 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL23540853 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850120-A | Preparation method of alcohol alpha-carbon hydrogen bond alkylated compound | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |