SCHEMBL7442302

SCHEMBL7442302

O=C1CC(OCc2ccc(OCc3ccccc3)cc2)CN1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.55
MAOA P21397 3/20 0.46
PTPN1 P18031 2/20 0.46
HPGD P15428 1/20 0.46
POLB P06746 1/20 0.46
PDE4A P27815 1/20 0.46
PDE4B Q07343 1/20 0.46
PDE4C Q08493 1/20 0.46
PDE4D Q08499 1/20 0.46
GSTP1 P09211 1/20 0.44
CREBBP Q92793 1/20 0.44
BCHE P06276 1/20 0.44
PPARG P37231 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2173563 0.90 PDE4A (0.46) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL7420548 0.90 PDE4A (0.46) MAOBPDE4APDE4BPDE4CPDE4D
SCHEMBL21026697 0.79 CARM1 (0.41) MAOBMAOAMEN1KMT2A
SCHEMBL18472041 0.79 CARM1 (0.41) MAOBMAOAMEN1KMT2A
SCHEMBL19885198 0.79 CARM1 (0.41) MAOBMAOAMEN1KMT2A
SCHEMBL20869229 0.72 MAOB (0.45) MAOBMAOAGSTP1LMNACYP1A2
SCHEMBL27767020 0.71 MAOB (0.56) MAOBMAOAPTPN1HPGDPOLB
SCHEMBL5207455 0.71 MAOB (0.56) MAOBMAOAPTPN1HPGDPOLB
SCHEMBL2297346 0.71 MAOB (0.59) MAOBMAOAPDE4APDE4BPDE4C
SCHEMBL2299358 0.71 MAOB (0.59) MAOBMAOAPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526535-A1 CYCLIC HYDROXAMIC ACIDS AND THEIR USE. ORION YHTYMAE OY (FI) 1993-02-10 EP disclosed
WO-1991016303-A1 CYCLIC HYDROXAMIC ACIDS AND THEIR USE Orion-Yhtymä Oy (FI) 1991-10-31 WO disclosed