Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869226 | 0.73 | MAOA (0.48) | MAOBLMNAKCNH2CYP1A2PTGS1 | |
| SCHEMBL7442302 | 0.72 | MAOB (0.55) | MAOBLMNAGSTP1CYP1A2PTGS1 | |
| SCHEMBL20869231 | 0.72 | TP53 (0.41) | MAOBTP53LMNAKCNH2CYP1A2 | |
| SCHEMBL10272647 | 0.72 | MRGPRX4 (0.64) | MAOBLMNAKCNH2CYP1A2PTGS1 | |
| SCHEMBL20455786 | 0.72 | MAOB (0.61) | MAOBLMNAGSTP1CYP1A2PTGS1 | |
| SCHEMBL16937202 | 0.72 | OPRM1 (0.53) | MAOBTP53LMNAKCNH2TNKS2 | |
| SCHEMBL24798064 | 0.71 | MRGPRX4 (0.50) | MAOBTP53MMP13LMNAKCNH2 | |
| SCHEMBL2149901 | 0.71 | MRGPRX4 (0.50) | MAOBTP53MMP13LMNAKCNH2 | |
| SCHEMBL2150597 | 0.71 | MRGPRX4 (0.50) | MAOBTP53MMP13LMNAKCNH2 | |
| SCHEMBL16874617 | 0.71 | TP53 (0.47) | MAOBTP53MMP13LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688118-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |
| US-20200263091-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
| WO-2019063585-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-04-04 | — | — | WO | disclosed |