Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420548 | 1.00 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DCTSL | |
| SCHEMBL7442302 | 0.90 | MAOB (0.55) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL19885198 | 0.84 | CARM1 (0.41) | MAOBCARM1PRMT6 | |
| SCHEMBL18472041 | 0.84 | CARM1 (0.41) | MAOBCARM1PRMT6 | |
| SCHEMBL21026697 | 0.84 | CARM1 (0.41) | MAOBCARM1PRMT6 | |
| SCHEMBL425330 | 0.77 | CTSL (0.50) | CTSLCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL581885 | 0.74 | CTSL (0.51) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL16699631 | 0.74 | LMNA (0.55) | PDE4APDE4BPDE4CPDE4DCTSL | |
| SCHEMBL4059320 | 0.74 | CREBBP (0.45) | CTSLCTSBCTSKLMNAPSEN1 | |
| SCHEMBL3740260 | 0.74 | HRH1 (0.47) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247578-B2 | Process for production of aralkyloxypyrrolidine derivative | KANEKA CORPORATION (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8242285-B2 | N-tert-butoxycarbonyl-2-pyrrolidinones and production method thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORPORATION (JP) | 2011-09-15 | — | — | US | disclosed |
| US-7973176-B2 | Process for production of aralkyloxypyrrolidine derivative | KANEKA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| EP-1947083-B1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORP (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100280259-A1 | N-Tert-Butoxycarbonyl-2-Pyrrolidinones and Production Method Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20090163722-A1 | N-TERT-BUTOXYCARBONYL-2-PYRROLIDINONES AND PRODUCTION METHOD THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
| CN-101415676-A | N-tert-butoxycarbonyl-2-pyrrolidinone compounds and method for producing the same | SUMITOMO CHEMICAL CO (JP) | 2009-04-22 | — | — | CN | disclosed |
| EP-2008999-A1 | N-TERT-BUTOXYCARBONYL-2-PYRROLIDINONES AND PROCESS FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | KANEKA CORPORATION (JP) | 2008-12-11 | — | — | US | disclosed |
| EP-1947083-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | Kaneka Corporation (JP) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | HPD, HAAO, ARL1 | PDE4A 1938/4885PDE4B 2766/4885PDE4C 2200/4885 |
| US-20090163722-A1 | N-TERT-BUTOXYCARBONYL-2-PYRROLIDINONES AND PRODUCTION METHOD THEREOF | TERT, CBR1, TELO2 | PDE4A 4686/4885PDE4B 4683/4885PDE4C 4741/4885 |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | HPD, HAAO, ARL1 | PDE4A 1938/4885PDE4B 2766/4885PDE4C 2200/4885 |
| US-20100280259-A1 | N-Tert-Butoxycarbonyl-2-Pyrrolidinones and Production Method Thereof | TERT, CBR1, TELO2 | PDE4A 4686/4885PDE4B 4683/4885PDE4C 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.