Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440652 | 0.90 | CTSK (0.47) | CTSKCTSSGABRB1GABRB2KLK5 | |
| SCHEMBL7441752 | 0.89 | CTSK (0.45) | CTSKCTSSPOLBGABRB1GABRB2 | |
| SCHEMBL7430555 | 0.87 | METAP2 (0.47) | CTSKCTSSMEN1KMT2AGABRB1 | |
| SCHEMBL7429952 | 0.87 | CTSK (0.45) | CTSKCTSSGABRB1GABRB2KLK5 | |
| SCHEMBL7442604 | 0.87 | CTSK (0.45) | CTSKCTSSGABRB1GABRB2KLK5 | |
| SCHEMBL7431637 | 0.85 | CTSK (0.44) | CTSKCTSSGABRB1GABRB2KLK5 | |
| SCHEMBL7443768 | 0.85 | CTSK (0.44) | CTSKCTSSGABRB1GABRB2KLK5 | |
| SCHEMBL17106932 | 0.83 | CTSK (0.65) | CTSKCTSSPOLBCTSLCTSB | |
| SCHEMBL17106924 | 0.83 | CTSK (0.65) | CTSKCTSSPOLBCTSLCTSB | |
| SCHEMBL17106933 | 0.83 | CTSK (0.65) | CTSKCTSSPOLBCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |