Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433707 | 0.91 | GPR119 (0.45) | KDM4EPKMGPR119LIMK2 | |
| SCHEMBL24569257 | 0.85 | ACHE (0.55) | KDM4EPKMGPR119TGFBR1 | |
| SCHEMBL7436837 | 0.77 | GPR119 (0.48) | KDM4EPKMGPR119TSHR | |
| SCHEMBL7440251 | 0.75 | KDM4E (0.53) | KDM4EPKMGPR119KMT2A | |
| SCHEMBL24569259 | 0.72 | KDM4E (0.54) | KDM4EPKMGPR119TGFBR1 | |
| SCHEMBL1252952 | 0.70 | KDM4E (0.57) | KDM4EPKMGPR119KMT2A | |
| SCHEMBL22770407 | 0.70 | USP30 (0.43) | GPR119TSHRKMT2A | |
| SCHEMBL29605324 | 0.70 | USP30 (0.43) | GPR119TSHRKMT2A | |
| SCHEMBL19067521 | 0.70 | KDM4E (0.51) | KDM4EPKMGPR119KMT2A | |
| SCHEMBL12736015 | 0.69 | KDM4E (0.56) | KDM4EPKMGPR119KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525617-A | ANTICOAGULANT | MERCK & CO., INC. (US) | 1996-06-11 | — | — | US | disclosed |