Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442572 | 1.00 | TNFRSF1A (0.56) | TNFRSF1AEPHX2TTRAPPCA12 | |
| SCHEMBL5712559 | 0.85 | GABBR2 (0.64) | TNFRSF1AEPHX2TTRAPPCA12 | |
| SCHEMBL5712558 | 0.85 | GABBR2 (0.64) | TNFRSF1AEPHX2TTRAPPCA12 | |
| SCHEMBL29192602 | 0.79 | APP (0.56) | TNFRSF1AAPPHTR1AHTR2C | |
| SCHEMBL2433926 | 0.78 | ALDH1A1 (0.72) | TNFRSF1AEPHX2CA1CA2KDM4E | |
| SCHEMBL2433925 | 0.78 | ALDH1A1 (0.72) | TNFRSF1AEPHX2CA1CA2KDM4E | |
| SCHEMBL6916935 | 0.78 | TNFRSF1A (0.50) | TNFRSF1ACA1CA2GABBR2GABBR1 | |
| SCHEMBL5576304 | 0.78 | TNFRSF1A (0.80) | TNFRSF1ACA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7065034 | 0.78 | TNFRSF1A (0.50) | TNFRSF1ACA1CA2GABBR2GABBR1 | |
| SCHEMBL7060721 | 0.77 | TNFRSF1A (0.49) | TNFRSF1ACA1CA2GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526535-B1 | CYCLIC HYDROXAMIC ACIDS AND THEIR USE | ORION YHTYMAE OY (FI) | 1995-09-27 | — | — | EP | disclosed |
| US-5356923-A | 1-hydroxy-4(3-cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone and anti-hypertensive use thereof | ORION-YHTYMA OY (FI) | 1994-10-18 | — | — | US | disclosed |
| EP-0526535-A1 | CYCLIC HYDROXAMIC ACIDS AND THEIR USE. | ORION YHTYMAE OY (FI) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991016303-A1 | CYCLIC HYDROXAMIC ACIDS AND THEIR USE | Orion-Yhtymä Oy (FI) | 1991-10-31 | — | — | WO | disclosed |