Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.54 |
| ▸ | ESR1 | P03372 | 12/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913405 | 0.88 | ESR2 (0.57) | ESR2ESR1CYP19A1GRIN1GRIN2B | |
| SCHEMBL19116602 | 0.85 | GFRA3 (0.51) | ESR2ESR1MEN1KMT2APGR | |
| SCHEMBL8348394 | 0.83 | ESR1 (0.54) | ESR2ESR1CYP19A1DRD2DRD3 | |
| SCHEMBL28033988 | 0.83 | ESR1 (0.54) | ESR2ESR1CYP19A1DRD2DRD3 | |
| SCHEMBL9281232 | 0.82 | MAP3K14 (0.51) | TSHRPGRSLC6A4HTR2B | |
| SCHEMBL29959450 | 0.82 | MAP3K14 (0.51) | TSHRPGRSLC6A4HTR2B | |
| SCHEMBL1693312 | 0.82 | MAP3K14 (0.51) | TSHRPGRSLC6A4HTR2B | |
| SCHEMBL15909359 | 0.82 | MAP3K14 (0.51) | TSHRPGRSLC6A4HTR2B | |
| SCHEMBL8034552 | 0.78 | ESR1 (0.53) | ESR2ESR1CYP19A1DRD2DRD3 | |
| SCHEMBL3202300 | 0.78 | SRD5A1 (0.45) | PGRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995015325-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-08 | — | — | WO | claimed |
| CN-116234546-A | GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases | 嘉兴优博生物技术有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-3082786-B1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME (US) | 2021-10-27 | — | — | EP | disclosed |
| CN-108292064-A | Alignment films and liquid crystal display device | 夏普株式会社 | 2018-07-17 | — | — | CN | disclosed |
| CN-104903363-B | Monomer, liquid-crystal composition, the manufacture method of liquid crystal display device and liquid crystal display device | 夏普株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-107615144-A | Liquid crystal display device and alignment films | 夏普株式会社 | 2018-01-19 | — | — | CN | disclosed |
| CN-107037635-A | The manufacture method of liquid crystal display device | 夏普株式会社 | 2017-08-11 | — | — | CN | disclosed |
| CN-106873248-A | Liquid crystal display panel and liquid crystal display device | 夏普株式会社 | 2017-06-20 | — | — | CN | disclosed |
| CN-106662767-A | Liquid-crystal display | 夏普株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-103765305-B | Liquid crystal display panel and liquid crystal display device | 夏普株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-103919705-A | Composite hair dyeing powder prepared from indigofera tinctoria plant | ZHANG XIANWEN | 2014-07-16 | — | — | CN | disclosed |
| US-5395847-A | Angiotensin II receptor antagonists; useful in regulating hypertension, treatment of congestive heart failure, renal failure, and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-07 | — | — | US | disclosed |
| US-4265892-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4202900-A | Derivatives of penam-3-carboxylic acid and a pharmaceutical composition containing the same | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4067979-A | Cephalosporins having an α-acyloxyacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4015000-A | 6-Acylamino-penam-3-carboxylic and 7-acylamino-3-cephem-4-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-4012524-A | DIURETICS, SALURETICS, HYPOURICEMICS, HYPOTENSIVES, ANTIEDEMICS | MERCK & CO., INC. (US) | 1977-03-15 | — | — | US | disclosed |
| US-4012524-A | DIURETICS, SALURETICS, HYPOURICEMICS, HYPOTENSIVES, ANTIEDEMICS | MERCK & CO., INC. (US) | 1977-03-15 | — | — | US | disclosed |