Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.57 |
| ▸ | ESR1 | P03372 | 9/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442811 | 0.88 | ESR2 (0.54) | ESR2ESR1GRIN1GRIN2BPGR | |
| SCHEMBL6409578 | 0.85 | ESR1 (0.47) | ESR2ESR1CYP19A1MAOAMAOB | |
| SCHEMBL23850632 | 0.83 | PYGL (0.52) | ESR2ESR1PGRPYGLTSHR | |
| SCHEMBL15778906 | 0.83 | PYGL (0.52) | ESR2ESR1PGRPYGLTSHR | |
| SCHEMBL8274690 | 0.79 | ESR1 (0.55) | ESR2ESR1CYP19A1HSD17B1SHBG | |
| SCHEMBL30835166 | 0.79 | ESR1 (0.55) | ESR2ESR1PGRCYP19A1HSD17B1 | |
| SCHEMBL12401916 | 0.79 | ESR1 (0.55) | ESR2ESR1PGRCYP19A1HSD17B1 | |
| SCHEMBL32665639 | 0.79 | ESR1 (0.55) | ESR2ESR1CYP19A1HSD17B1SHBG | |
| SCHEMBL7074968 | 0.79 | PGR (0.45) | ESR2ESR1PGRPYGL | |
| SCHEMBL21870100 | 0.79 | UGT2B17 (0.51) | ESR2ESR1PGRPYGLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |