Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409578 | 0.88 | ESR1 (0.47) | ESR1ESR2MAOAMAOBCYP19A1 | |
| SCHEMBL1520909 | 0.86 | ESR1 (0.50) | ESR1ESR2MAOAMAOBCYP19A1 | |
| SCHEMBL7442811 | 0.83 | ESR2 (0.54) | ESR1ESR2CYP19A1DRD2DRD3 | |
| SCHEMBL9276752 | 0.78 | HTR2A (0.46) | DRD2OPRK1 | |
| SCHEMBL3638981 | 0.78 | HTR2A (0.46) | DRD2OPRK1 | |
| SCHEMBL25015456 | 0.78 | ESR1 (0.53) | ESR1ESR2MAOAMAOBCYP19A1 | |
| SCHEMBL836185 | 0.78 | UGT2B17 (0.46) | DRD2CYP2D6SLC6A4 | |
| SCHEMBL17571270 | 0.78 | UGT2B17 (0.46) | DRD2CYP2D6SLC6A4 | |
| SCHEMBL22547852 | 0.78 | CHRM4 (0.40) | ESR1ESR2MAOAMAOBCYP19A1 | |
| SCHEMBL1372731 | 0.78 | DRD2 (0.55) | ESR1ESR2MAOAMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903363-B | Monomer, liquid-crystal composition, the manufacture method of liquid crystal display device and liquid crystal display device | 夏普株式会社 | 2018-05-04 | — | — | CN | disclosed |
| US-5952326-A | Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5698550-A | Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1997-12-16 | — | — | US | disclosed |
| EP-0441515-B1 | Tetralin and chroman derivatives in the treatment of asthma, arthritis and related diseases | PFIZER (US) | 1995-10-04 | — | — | EP | disclosed |
| EP-0441515-A1 | Tetralin and chroman derivatives in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |