Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217147 | 0.74 | MEN1 (0.46) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL6217205 | 0.74 | MEN1 (0.46) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL7433696 | 0.74 | SLC6A2 (0.35) | MEN1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL14067275 | 0.73 | CHRNA7 (0.64) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL6216542 | 0.72 | MEN1 (0.47) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL6219114 | 0.72 | MEN1 (0.47) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL7180212 | 0.71 | SIGMAR1 (0.58) | CHRNA7KCNH2HTR1ASIGMAR1DRD2 | |
| SCHEMBL28697423 | 0.70 | USP2 (0.50) | ADRA2AADRA2BADRA2CCHRNA7MEN1 | |
| SCHEMBL11762555 | 0.70 | KCNH2 (0.69) | CHRNA7MEN1KMT2ADRD4KCNH2 | |
| SCHEMBL6385783 | 0.70 | KCNH2 (0.69) | ADRA2AADRA2BADRA2CCHRNA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479665-A2 | 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |