Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22725302 | 0.93 | MAPT (0.33) | MEN1KMT2ATSHRMAPTATM | |
| SCHEMBL22725319 | 0.93 | MEN1 (0.36) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL951043 | 0.91 | MAPT (0.34) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL18761051 | 0.86 | KDM1A (0.36) | MAPTATMGAA | |
| SCHEMBL17066768 | 0.77 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL25642348 | 0.77 | KDM4E (0.41) | SLC6A2SLC6A4SLC6A3TSHRGAA | |
| SCHEMBL7442901 | 0.74 | ADRA2A (0.48) | MEN1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL4874234 | 0.74 | ALDH1A1 (0.39) | TSHRMAPTALDH1A1 | |
| SCHEMBL22444527 | 0.74 | ALDH1A1 (0.39) | TSHRMAPTALDH1A1 | |
| SCHEMBL2022361 | 0.74 | ALDH1A1 (0.39) | TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479665-A2 | 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |