Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 9/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | CTSE | P14091 | 2/20 | 0.40 |
| ▸ | PGC | P20142 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079969 | 0.78 | SLC6A3 (0.56) | HTR3ARENSLC6A3 | |
| SCHEMBL7079965 | 0.78 | SLC6A3 (0.56) | HTR3ARENSLC6A3 | |
| SCHEMBL27594967 | 0.77 | SSTR4 (0.44) | HTR3ARENCTSDCTSEPGC | |
| Hydrochloric Acid SCHEMBL7084155 | 0.77 | SLC6A3 (0.55) | HTR3ARENSLC6A3 | |
| Hydrochloric Acid SCHEMBL7084158 | 0.77 | SLC6A3 (0.55) | HTR3ARENSLC6A3 | |
| SCHEMBL4308696 | 0.73 | GBA1 (0.52) | HTR3ASLC6A3 | |
| SCHEMBL7441689 | 0.72 | ALDH1A1 (0.42) | SSTR4 | |
| SCHEMBL2636787 | 0.72 | ALDH1A1 (0.42) | SSTR4 | |
| SCHEMBL13389890 | 0.72 | PRMT5 (0.45) | SLC6A3 | |
| SCHEMBL13389337 | 0.72 | PRMT5 (0.45) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975595-A1 | ANALOGS OF COCAINE | GEORGETOWN UNIVERSITY (US) | 2000-02-02 | — | — | EP | claimed |
| WO-1998045263-A1 | ANALOGS OF COCAINE | GEORGETOWN UNIVERSITY (US) | 1998-10-15 | — | — | WO | claimed |
| EP-1119553-A1 | MONOMERIC AND DIMERIC HETEROCYCLES, AND THERAPEUTIC USES THEREOF | GEORGETOWN UNIVERSITY (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020390-A1 | MONOMERIC AND DIMERIC HETEROCYCLES, AND THERAPEUTIC USES THEREOF | GEORGETOWN UNIVERSITY (US) | 2000-04-13 | — | — | WO | disclosed |
| EP-0975595-A1 | ANALOGS OF COCAINE | GEORGETOWN UNIVERSITY (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045263-A1 | ANALOGS OF COCAINE | GEORGETOWN UNIVERSITY (US) | 1998-10-15 | — | — | WO | disclosed |