Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404524 | 1.00 | POLB (0.47) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL1900944 | 0.86 | L3MBTL1 (0.49) | L3MBTL1KMT2AKDM4EKCNK3KCNK9 | |
| SCHEMBL22283800 | 0.84 | MEN1 (0.49) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL22144400 | 0.84 | MEN1 (0.49) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL10575353 | 0.84 | POLB (0.44) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL1822261 | 0.83 | CA1 (0.39) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL2065727 | 0.83 | PPARG (0.43) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL6400516 | 0.82 | KMT2A (0.55) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL13170107 | 0.82 | POLB (0.49) | POLBHTTNPSR1L3MBTL1KMT2A | |
| SCHEMBL503436 | 0.82 | KMT2A (0.55) | POLBHTTNPSR1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118218027-A | Application of polydentate ligand/ruthenium catalyst and method for preparing diol compound by hydrogenation reaction of alpha-hydroxy ester | 郑州大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118218027-A | Application of polydentate ligand/ruthenium catalyst and method for preparing diol compound by hydrogenation reaction of alpha-hydroxy ester | 郑州大学 | 2024-06-21 | — | — | CN | disclosed |
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| EP-0146893-B1 | BENZOTHIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-24 | — | — | EP | disclosed |
| US-4595685-A | Pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |
| EP-0146893-A2 | Benzothiazine derivatives, processes for their preparation, medicaments containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-03 | — | — | EP | disclosed |