Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524834 | 0.85 | L3MBTL1 (0.62) | ALDH1A1GAAALOX12SMN1; SMN2GLA | |
| SCHEMBL3231208 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAACA12CA1 | |
| SCHEMBL600772 | 0.83 | KDM4E (0.62) | ALDH1A1KDM4EGAACA12CA1 | |
| SCHEMBL29395845 | 0.83 | KDM4E (0.62) | ALDH1A1KDM4EGAACA12CA1 | |
| Methane SCHEMBL11380092 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAACA12CA1 | |
| SCHEMBL28491600 | 0.82 | NR1H4 (0.56) | ALDH1A1KDM4EGAAALOX12SMN1; SMN2 | |
| SCHEMBL8858796 | 0.82 | ERCC5 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7446526 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EGAACA12CA1 | |
| SCHEMBL29238224 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4EGAACA12CA1 | |
| Benzoic Acid SCHEMBL15670727 | 0.81 | CA12 (0.58) | ALDH1A1KDM4EGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |