Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776471 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL11510398 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL3131180 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL3442058 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL740593 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL27450687 | 0.98 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL8151244 | 0.95 | LMNA (0.50) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL738259 | 0.91 | LMNA (0.48) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL10338053 | 0.90 | FFAR4 (0.46) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL8157897 | 0.88 | LMNA (0.46) | TSHRLMNANFKB1PMP22GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137978-B2 | Diagnostic method for biomarkers of adverse coronary events | SAINT LOUIS UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110091980-A1 | DIAGNOSTIC METHOD FOR BIOMARKERS OF ADVERSE CORONARY EVENTS | SAINT LOUIS UNIVERSITY (US) | 2011-04-21 | — | — | US | disclosed |