SCHEMBL738259

SCHEMBL738259

O=C(O)CCCC(Cl)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
FOLH1 Q04609 3/20 0.46
TSHR P16473 2/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
ENPEP Q07075 2/20 0.45
GSTK1 Q9Y2Q3 2/20 0.45
TET2 Q6N021 3/20 0.42
KDM4A O75164 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
KDM2A Q9Y2K7 2/20 0.42
TET3 O43151 1/20 0.42
CAMK2A Q9UQM7 1/20 0.42
CYP1A2 P05177 3/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GSR P00390 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157897 0.98 LMNA (0.46) LMNASLC22A6FOLH1TSHRNFKB1
SCHEMBL27450687 0.93 LMNA (0.52) LMNASLC22A6FOLH1TSHRNFKB1
SCHEMBL3131180 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL744348 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL9776471 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL8151244 0.91 LMNA (0.50) LMNASLC22A6FOLH1TSHRNFKB1
SCHEMBL11510398 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL740593 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL3442058 0.91 TSHR (0.55) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL3086060 0.84 FOLH1 (0.56) LMNAFOLH1TSHRTET2KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103952114-A Polyamide adhesive for card fabrication TIANJIN FENGDEYIKANG NEW MATERIAL TECHNOLOGY CO LTD 2014-07-30 CN claimed
CN-103937440-A Preparation method of polyamide adhesive for card fabrication TIANJIN FENGDEYIKANG NEW MATERIAL TECHNOLOGY CO LTD 2014-07-23 CN claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed
US-11999688-B2 Method for producing dicarboxylic acid DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2024-06-04 US disclosed
CN-116178391-A Forward allosteric modulators of muscarinic acetylcholine receptor M4 范德比尔特大学 2023-05-30 CN disclosed
US-20210147331-A1 METHOD FOR PRODUCING DICARBOXYLIC ACID DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2021-05-20 US disclosed
CN-110615736-B Preparation method of dicarboxylic acid 中国科学院大连化学物理研究所 2021-01-26 CN disclosed
WO-2020253077-A1 USE OF DICARBOXYLIC ACID COMPOUNDS FOR CONTROLLING PLANT DISEASES CHINA AGRICULTURAL UNIVERSITY (CN) 2020-12-24 WO disclosed
CN-110615736-A Preparation method of dicarboxylic acid 中国科学院大连化学物理研究所 2019-12-27 CN disclosed
WO-2019242038-A1 METHOD FOR PREPARING DICARBOXYLIC ACID 中国科学院大连化学物理研究所 2019-12-26 WO disclosed
CN-103952114-A Polyamide adhesive for card fabrication TIANJIN FENGDEYIKANG NEW MATERIAL TECHNOLOGY CO LTD 2014-07-30 CN disclosed
WO-2002033396-A1 LIGAND BASED SOLUTION ASSAY FOR LOW CONCENTRATION ANALYTES SAUNDERS ALEX M (US) 2002-04-25 WO disclosed
CN-1261116-A Composite thickening agent for printing with reactive dye SHENYANG GENERAL INST OF CHEMI (CN) 2000-07-26 CN disclosed
US-4883886-A MULTISTAGE ADDITION OF REACTANTS, HYDANTOIN COMPOUND TO INHIBIT BY-PRODUCT FORMATION AMOCO CORPORATION (US) 1989-11-28 US disclosed
US-4377490-A CYANOACRYLATE, ETHERS, ALCOHOLS, ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-22 US disclosed
US-4206019-A ELECTRODEPOSITION IN PRESENCE OF A CARBOXYLIC ACID, SULFATE ION AND A FLUORIDE CATALYST M&T CHEMICALS INC. (US) 1980-06-03 US disclosed
US-4086251-A POLYPROPYLENE, POLYBUTYLENE WITH AN ANHYDRIDE STANDARD OIL COMPANY (INDIANA) (US) 1978-04-25 US disclosed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US disclosed
US-4008168-A Polybutene composition containing halogen-containing additives and use thereof STANDARD OIL COMPANY (INDIANA) (US) 1977-02-15 US disclosed
US-3954812-A REACTING POLYBUTENE AND MALEIC ANHYDRIDE STANDARD OIL COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147331-A1 METHOD FOR PRODUCING DICARBOXYLIC ACID MCCC2, PCCA, PC LMNA 4149/4885SLC22A6 1328/4885FOLH1 2951/4885
US-11999688-B2 Method for producing dicarboxylic acid MCCC2, PCCA, PC LMNA 4149/4885SLC22A6 1328/4885FOLH1 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.