Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444675 | 0.87 | F2 (0.61) | F2 | |
| SCHEMBL6965070 | 0.87 | LTA4H (0.53) | LTA4HHTTF2MCHR1KCNH2 | |
| SCHEMBL7452057 | 0.83 | HRH3 (0.54) | LTA4HCD274F2HRH3KDM4E | |
| SCHEMBL6968891 | 0.83 | MCHR1 (0.48) | LTA4HCD274HTTF2MCHR1 | |
| SCHEMBL7774139 | 0.82 | F2 (0.68) | LTA4HF2 | |
| SCHEMBL7447052 | 0.81 | CD274 (0.55) | CD274F2HRH3KDM4E | |
| SCHEMBL7355874 | 0.80 | CD274 (0.54) | LTA4HCD274F2HRH3KDM4E | |
| SCHEMBL7446083 | 0.80 | F2 (0.60) | LTA4HCD274F2KCNH2HRH3 | |
| SCHEMBL7349015 | 0.80 | CD274 (0.47) | CD274HTTF2HRH3KDM4E | |
| SCHEMBL7353107 | 0.79 | HRH3 (0.48) | LTA4HCD274F2KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |