Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444470 | 0.82 | CAPN1 (0.58) | CAPN1 | |
| SCHEMBL17275375 | 0.79 | PTPRA (0.54) | FDPSPTPRACAPN1KMT2ASMN1; SMN2 | |
| SCHEMBL27264324 | 0.78 | PTPRA (0.49) | FDPSPTPRAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL7863671 | 0.78 | PTPRA (0.49) | FDPSPTPRAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL7862733 | 0.78 | PTPRA (0.49) | FDPSPTPRAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL7453772 | 0.76 | CTSK (0.44) | CAPN1POLB | |
| SCHEMBL3759700 | 0.75 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7109563 | 0.72 | CTSK (0.48) | PTPRACYP1A2HDAC6HDAC1 | |
| SCHEMBL17167272 | 0.71 | FDPS (0.46) | FDPSPTPRASMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL13349692 | 0.71 | PTPRA (0.42) | FDPSPTPRACAPN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946509-A1 | NOVEL HETEROCYCLICALLY SUBSTITUTED BENZAMIDES AND THEIR USE IN FIGHTING DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025899-A1 | NOVEL HETEROCYCLICALLY SUBSTITUTED BENZAMIDES AND THEIR USE IN FIGHTING DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |