Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175655 | 0.99 | CA1 (0.47) | CA1CA2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8175651 | 0.90 | CA1 (0.43) | CA1CA2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7393277 | 0.89 | PPARA (0.52) | L3MBTL1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8181521 | 0.88 | PPARA (0.51) | L3MBTL1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7431686 | 0.82 | AKR1C3 (0.43) | L3MBTL1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8181516 | 0.82 | PPARA (0.42) | CA1CA2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8174950 | 0.81 | AKR1C3 (0.43) | L3MBTL1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7395385 | 0.81 | L3MBTL1 (0.46) | L3MBTL1TUBB4ATUBBTUBB4BTUBB3 | |
| SCHEMBL7399212 | 0.78 | L3MBTL1 (0.43) | L3MBTL1TUBB4ATUBBTUBB4BTUBB3 | |
| SCHEMBL7394624 | 0.77 | STING1 (0.50) | L3MBTL1ALDH1A1KDM4EGAATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955299-B1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-13 | — | — | EP | disclosed |
| EP-0955299-A1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-11-10 | — | — | EP | disclosed |