Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431686 | 0.99 | AKR1C3 (0.43) | AKR1C3AKR1C2HCAR2KMT2AMEN1 | |
| SCHEMBL8174946 | 0.90 | L3MBTL1 (0.40) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7431734 | 0.83 | L3MBTL1 (0.39) | AKR1C3AKR1C2KMT2AMEN1L3MBTL1 | |
| SCHEMBL8175655 | 0.82 | CA1 (0.47) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7391101 | 0.82 | CA12 (0.44) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8181521 | 0.82 | PPARA (0.51) | AKR1C3AKR1C2KMT2AMEN1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL8176215 | 0.81 | CA12 (0.43) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8176216 | 0.81 | CA12 (0.43) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7444160 | 0.81 | CA1 (0.48) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7393277 | 0.81 | PPARA (0.52) | AKR1C3AKR1C2KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |