Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.89 |
| ▸ | CTSL | P07711 | 16/20 | 0.89 |
| ▸ | CTSS | P25774 | 13/20 | 0.89 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444598 | 0.94 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7471864 | 0.91 | CTSK (0.89) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7474895 | 0.91 | CTSK (0.89) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7467496 | 0.88 | CTSL (0.84) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7448033 | 0.88 | CTSL (0.83) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7452759 | 0.87 | CTSK (0.81) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7448094 | 0.87 | CTSK (0.81) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7442508 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7463735 | 0.85 | CTSK (0.81) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7473495 | 0.85 | CTSK (0.81) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | claimed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | claimed |
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | disclosed |
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |