Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HEXA | P06865 | 1/20 | 0.44 |
| ▸ | HEXB | P07686 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963204 | 0.83 | ALDH1A1 (0.52) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL31425560 | 0.83 | ALDH1A1 (0.52) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL368756 | 0.81 | ALDH1A1 (0.65) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL4309242 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL21801787 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL10052097 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL876560 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1MAPTNPSR1CASP3CA12 | |
| SCHEMBL1435917 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GLSMAPTNPSR1CA12 | |
| SCHEMBL30852760 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GLSMAPTNPSR1CA12 | |
| SCHEMBL28989527 | 0.77 | ALDH1A1 (0.59) | ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511270-A1 | NEW THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010657-A1 | NEW THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-07-25 | — | — | WO | disclosed |