Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HEXA | P06865 | 1/20 | 0.42 |
| ▸ | HEXB | P07686 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368756 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL7444648 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL13587642 | 0.78 | CASP3 (0.51) | ALDH1A1MAPTNPSR1CASP3CA12 | |
| SCHEMBL21801787 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL14691850 | 0.76 | GLS (0.50) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL5798482 | 0.75 | MAPK1 (0.58) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL30268729 | 0.75 | MAPK1 (0.58) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL5798484 | 0.75 | MAPK1 (0.58) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL6153732 | 0.75 | MAPK1 (0.58) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL30242673 | 0.75 | ALDH1A1 (0.59) | ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040761-B2 | Branched hetero polyethylene glycol and intermediate | NOF CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | NOF CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | F12, FGB, F13B | ALDH1A1 3626/4885GLS 1984/4885MAPT 2800/4885 |
| US-10040761-B2 | Branched hetero polyethylene glycol and intermediate | F12, FGB, F10 | ALDH1A1 3665/4885GLS 2135/4885MAPT 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.