Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437197 | 0.87 | ITGB3 (0.41) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7437191 | 0.87 | ITGB3 (0.41) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7444913 | 0.87 | ESR1 (0.46) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7448790 | 0.79 | ITGB3 (0.55) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7435906 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7435901 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| Trifluoroacetic Acid SCHEMBL7440547 | 0.76 | ITGB3 (0.50) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| Trifluoroacetic Acid SCHEMBL7444687 | 0.76 | ITGB3 (0.50) | KDM4EALDH1A1MEN1KMT2AITGB3 | |
| SCHEMBL7338379 | 0.74 | ITGB3 (0.54) | KDM4EALDH1A1MEN1KMT2AITGB3 | |
| SCHEMBL7338384 | 0.74 | ITGB3 (0.54) | KDM4EALDH1A1MEN1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |