Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CALCA | P06881 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444753 | 0.87 | KDM4E (0.40) | ESR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7441230 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7440112 | 0.76 | ESR1 (0.40) | ESR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7548362 | 0.76 | KDM4E (0.41) | ESR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7431827 | 0.75 | KMT2A (0.40) | ESR1KDM4EMEN1KMT2ACTSS | |
| SCHEMBL7448790 | 0.74 | ITGB3 (0.55) | KDM4EALDH1A1MEN1KMT2AHIF1A | |
| SCHEMBL7435155 | 0.73 | CTSS (0.42) | KDM4EALDH1A1MEN1KMT2ACTSS | |
| SCHEMBL7443501 | 0.73 | LMNA (0.46) | KDM4EALDH1A1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7440133 | 0.73 | ESR1 (0.39) | ESR1MEN1KMT2ACTSSCTSK | |
| SCHEMBL7435316 | 0.73 | GPR119 (0.57) | ALDH1A1LMNAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |