Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7442314 | 0.99 | F2 (0.39) | F2ITGB3ITGA2BTMPRSS15BRD4 | |
| SCHEMBL7445456 | 0.97 | F2 (0.41) | F2ITGB3ITGA2BTMPRSS15BRD4 | |
| Hydrochloric Acid SCHEMBL7448177 | 0.92 | F2 (0.39) | F2ITGB3ITGA2BTMPRSS15BRD4 | |
| Hydrochloric Acid SCHEMBL7445287 | 0.92 | F2 (0.45) | F2ITGB3ITGA2BTMPRSS15BRD4 | |
| SCHEMBL7445932 | 0.91 | F2 (0.41) | F2ITGB3ITGA2BTMPRSS15BRD4 | |
| SCHEMBL7453241 | 0.88 | F2 (0.48) | F2PRSS1 | |
| SCHEMBL7445263 | 0.88 | F2 (0.38) | F2ITGB3ITGA2BTMPRSS15 | |
| Hydrochloric Acid SCHEMBL7449466 | 0.87 | F2 (0.40) | F2ITGB3ITGA2BBRD4CREBBP | |
| SCHEMBL7445168 | 0.85 | F2 (0.51) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7449253 | 0.84 | F2 (0.50) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3343359-B2 | — | — | 2002-11-11 | — | — | JP | claimed |
| JP-2001509815-A | — | — | 2001-07-24 | — | — | JP | claimed |
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | claimed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | claimed |
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |