Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 11/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443452 | 0.92 | TMPRSS15 (0.36) | F2TMPRSS15ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7446256 | 0.92 | SMN1; SMN2 (0.38) | F2TMPRSS15ITGB3ITGA2B | |
| SCHEMBL7444769 | 0.88 | F2 (0.40) | F2TMPRSS15ITGB3ITGA2B | |
| SCHEMBL7453241 | 0.87 | F2 (0.48) | F2 | |
| Hydrochloric Acid SCHEMBL7442314 | 0.87 | F2 (0.39) | F2TMPRSS15ITGB3ITGA2B | |
| SCHEMBL7443815 | 0.86 | F2 (0.35) | F2TMPRSS15 | |
| SCHEMBL7445456 | 0.85 | F2 (0.41) | F2TMPRSS15ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7448332 | 0.85 | NQO2 (0.34) | TMPRSS15 | |
| SCHEMBL7446295 | 0.84 | KLK1 (0.44) | F2 | |
| SCHEMBL7445168 | 0.84 | F2 (0.51) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3343359-B2 | — | — | 2002-11-11 | — | — | JP | claimed |
| JP-2001509815-A | — | — | 2001-07-24 | — | — | JP | claimed |
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | claimed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | claimed |
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |