Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.56 |
| ▸ | NPY1R | P25929 | 3/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448671 | 0.90 | LTA4H (0.68) | LTA4HNPY1RSSTR2AURKBCHEK2 | |
| SCHEMBL7448799 | 0.89 | MEN1 (0.54) | LTA4HPSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL7445359 | 0.88 | LTA4H (0.56) | LTA4HPSMB1PSMB5PSMB2SSTR2 | |
| SCHEMBL23474877 | 0.86 | LTA4H (0.52) | LTA4HMEN1KMT2ACHEK2 | |
| SCHEMBL7446075 | 0.86 | LTA4H (0.75) | LTA4HNPY1RSSTR2AURKB | |
| SCHEMBL13761573 | 0.86 | LTA4H (0.52) | LTA4HMEN1KMT2ACHEK2 | |
| SCHEMBL23474908 | 0.86 | LTA4H (0.52) | LTA4HMEN1KMT2ACHEK2 | |
| SCHEMBL11447734 | 0.86 | LTA4H (0.67) | LTA4HNPY1R | |
| SCHEMBL7444811 | 0.82 | LTA4H (0.45) | LTA4HPSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL7116280 | 0.81 | LTA4H (0.70) | LTA4HCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | claimed |
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | disclosed |