Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444871 | 0.89 | LTA4H (0.56) | MEN1KMT2ALTA4HPSMB1PSMB5 | |
| SCHEMBL7445359 | 0.89 | LTA4H (0.56) | MEN1KMT2ALTA4HPSMB1PSMB5 | |
| SCHEMBL7444811 | 0.88 | LTA4H (0.45) | MEN1KMT2ALTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL23474908 | 0.87 | LTA4H (0.52) | MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL23474877 | 0.87 | LTA4H (0.52) | MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL13761573 | 0.87 | LTA4H (0.52) | MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL4965391 | 0.85 | LTA4H (0.64) | KMT2ALTA4H | |
| SCHEMBL7335832 | 0.83 | LTA4H (0.74) | LTA4H | |
| SCHEMBL7116280 | 0.82 | LTA4H (0.70) | LTA4H | |
| Hydrochloric Acid SCHEMBL7334091 | 0.82 | LTA4H (0.72) | KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | claimed |
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | disclosed |