Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442978 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BRAB9AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7448705 | 0.90 | ITGB3 (0.53) | ITGB3ITGA2BRAB9AALDH1A1GAA | |
| SCHEMBL7463087 | 0.87 | RAB9A (0.44) | RAB9AALDH1A1GAANPC1KMT2A | |
| SCHEMBL7445034 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BRAB9AALDH1A1GAA | |
| SCHEMBL7442972 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BSMN1; SMN2KMT2AF2R | |
| Hydrochloric Acid SCHEMBL7498752 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7441383 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BRAB9AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7439765 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BKMT2AF2R | |
| SCHEMBL7450244 | 0.79 | KMT2A (0.45) | ITGB3ITGA2BRAB9AALDH1A1GAA | |
| SCHEMBL7443415 | 0.78 | KMT2A (0.43) | RAB9AALDH1A1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |