Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445278 | 1.00 | MAPT (0.44) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL6609820 | 0.93 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL6609823 | 0.93 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL1465908 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL1465907 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL6438274 | 0.82 | KDM4A (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL6438285 | 0.82 | KDM4A (0.49) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL1626324 | 0.80 | TSHR (0.50) | ALDH1A1CYP3A4VCAM1TSHRMAPK1 | |
| SCHEMBL13365085 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1CYP3A4VCAM1TSHR | |
| SCHEMBL15592640 | 0.74 | MAPT (0.41) | MAPTALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706524-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 5- 2-(4-(BENZOISOTHIAZOL-3-YL)-PIPERAZIN-1-YL)ETHYL]-6-CHLORO-1,3-DIHYDRO-INDOL-2-ONE | PFIZER INC. (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995000510-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 5-[2-(4-(BENZOISOTHIAZOL-3-YL)-PIPERAZIN-1-YL)ETHYL]-6-CHLORO-1,3-DIHYDRO-INDOL-2-ONE | PFIZER INC. (US) | 1995-01-05 | — | — | WO | disclosed |