Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447138 | 0.90 | PTGER1 (0.54) | PTGER1TLR7 | |
| SCHEMBL7452183 | 0.89 | SMPD1 (0.54) | PTGER1SMN1; SMN2TLR7KMT2A | |
| SCHEMBL7447425 | 0.89 | NPC1 (0.52) | PTGER1SMN1; SMN2TLR7NPC1RAB9A | |
| SCHEMBL7443767 | 0.84 | PTGER1 (0.51) | PTGER1SMN1; SMN2TLR7NPC1RAB9A | |
| SCHEMBL7448167 | 0.83 | PTGER1 (0.50) | PTGER1SMN1; SMN2TLR7NPC1 | |
| SCHEMBL7087561 | 0.83 | PTGER1 (0.52) | PTGER1TLR7MAPT | |
| SCHEMBL7448062 | 0.82 | TLR7 (0.48) | PTGER1TLR7NPC1RAB9APOLB | |
| SCHEMBL7447783 | 0.82 | PTGER1 (0.49) | PTGER1TLR7 | |
| SCHEMBL6983082 | 0.81 | PTGER1 (0.56) | PTGER1TLR7MAPT | |
| SCHEMBL7448360 | 0.81 | TLR7 (0.50) | PTGER1SMN1; SMN2TLR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | claimed |
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |