Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.51 |
| ▸ | FEN1 | P39748 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686760 | 0.90 | ALOX5AP (0.55) | ALDH1A1ALOX5APFEN1LMNAGAA | |
| SCHEMBL6790764 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAHPGDGBA1CA1 | |
| SCHEMBL11629219 | 0.77 | KDM4E (0.53) | ALOX5APFEN1KDM4EGAATP53 | |
| SCHEMBL890706 | 0.75 | ALDH1A1 (0.61) | ALDH1A1GAAHPGDGBA1CA1 | |
| SCHEMBL3997838 | 0.74 | KDM4E (0.58) | ALOX5APFEN1KDM4EGAA | |
| SCHEMBL7862567 | 0.74 | GBA1 (0.74) | ALDH1A1GAAHPGDGBA1CA1 | |
| SCHEMBL23092657 | 0.73 | KDM4E (0.53) | ALDH1A1ALOX5APFEN1KDM4ELMNA | |
| SCHEMBL20946436 | 0.73 | ALDH1A1 (0.73) | ALDH1A1LMNAGAAHPGDGBA1 | |
| SCHEMBL29715407 | 0.73 | KDM4E (0.53) | ALDH1A1ALOX5APFEN1KDM4ELMNA | |
| SCHEMBL30513193 | 0.73 | ALDH1A1 (0.56) | ALDH1A1ALOX5APFEN1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946528-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028282-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |