Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652174 | 0.83 | HDAC1 (0.57) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL3857282 | 0.81 | ALOX5 (0.51) | METAP2METAP1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL8493313 | 0.80 | HDAC2 (0.59) | MEN1KMT2AMETAP2METAP1HDAC1 | |
| SCHEMBL13771296 | 0.79 | MEN1 (0.51) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL8161055 | 0.79 | HDAC1 (0.53) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL28314990 | 0.79 | ADRA2C (0.53) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL13771653 | 0.77 | HDAC1 (0.51) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL13771004 | 0.77 | HDAC1 (0.51) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL13771003 | 0.77 | HDAC1 (0.51) | MEN1KMT2AALPLALPIALPG | |
| SCHEMBL8159623 | 0.77 | HDAC1 (0.69) | CYP3A4HDAC1HDAC2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |