SCHEMBL7445523

SCHEMBL7445523

CSCC[C@H](NC(=O)[C@@H](CS)Cc1ccc(C)cc1)C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.71
FNTB P49356 4/20 0.71
PGGT1B P53609 4/20 0.71
LTA4H P09960 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7445517 1.00 FNTA (0.71) FNTAFNTBPGGT1BLTA4H
SCHEMBL7319175 0.90 LTA4H (0.73) FNTAFNTBPGGT1BLTA4H
SCHEMBL7319170 0.90 LTA4H (0.73) FNTAFNTBPGGT1BLTA4H
SCHEMBL7319165 0.90 LTA4H (0.73) FNTAFNTBPGGT1BLTA4H
SCHEMBL11121207 0.90 LTA4H (0.73) FNTAFNTBPGGT1BLTA4H
SCHEMBL9725019 0.90 LTA4H (0.73) FNTAFNTBPGGT1BLTA4H
SCHEMBL2875370 0.82 FNTA (0.52) FNTAFNTBPGGT1BLTA4H
SCHEMBL387498 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4H
SCHEMBL20558575 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4H
SCHEMBL392068 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929641-A DIURETICS, ANGIOTENSIN CONVERTING ENZYMES SCHERING CORPORATION (US) 1990-05-29 US disclosed