Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.73 |
| ▸ | FNTA | P49354 | 6/20 | 0.70 |
| ▸ | FNTB | P49356 | 6/20 | 0.70 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.70 |
| ▸ | MME | P08473 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121207 | 1.00 | LTA4H (0.73) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7319165 | 1.00 | LTA4H (0.73) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7319170 | 1.00 | LTA4H (0.73) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7319175 | 1.00 | LTA4H (0.73) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7445517 | 0.90 | FNTA (0.71) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL7445523 | 0.90 | FNTA (0.71) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL7327334 | 0.90 | FNTA (0.62) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7447698 | 0.90 | FNTA (0.62) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL11241067 | 0.89 | FNTA (0.60) | LTA4HFNTAFNTBPGGT1BMME | |
| SCHEMBL7325439 | 0.88 | MME (0.73) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |
| US-4567198-A | Ethanethioates and mercaptoamides and use thereof as analgesic and enkephalinase inhibitory compounds | ROUSSEL UCLAF (FR) | 1986-01-28 | — | — | US | disclosed |
| US-4432972-A | HYPOTENSIVE AGENTS, KANALGESICS, AND ANGIOTENSIN AND ENKEPHALIN INHIBITION | E. R. SQUIBB & SONS, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0066956-A1 | Enkephalinase enzyme inhibiting compounds | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |