Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | CTSC | P53634 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436798 | 1.00 | FCER2 (0.49) | FCER2RAB9AMMP1CTSCLMNA | |
| SCHEMBL28609690 | 0.76 | EPHX1 (0.60) | RAB9ACTSCLMNAPKMCYP2C19 | |
| SCHEMBL27875411 | 0.73 | EPHX1 (0.54) | FCER2LMNAPKMCYP2C19 | |
| SCHEMBL7306181 | 0.73 | CYP2C19 (0.50) | RAB9ACTSCLMNAPKMCYP2C19 | |
| SCHEMBL12464483 | 0.73 | FCER2 (0.52) | FCER2RAB9AMMP1CTSCHPGDS | |
| SCHEMBL7446381 | 0.71 | MME (0.57) | — | |
| SCHEMBL7437631 | 0.71 | MME (0.57) | — | |
| SCHEMBL29290747 | 0.70 | CYP2C19 (0.66) | RAB9ACTSCLMNAPKMCYP2C19 | |
| SCHEMBL7445888 | 0.70 | CYP2C19 (0.57) | RAB9ACTSCPKMCYP2C19ALDH1A1 | |
| SCHEMBL25721680 | 0.68 | RAB9A (0.54) | RAB9ACTSCLMNAPKMCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |