Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | HPGDS | O60760 | 3/20 | 0.51 |
| ▸ | CTSC | P53634 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448470 | 0.85 | CTRB1 (0.62) | FCER2MMP1CTRB1 | |
| SCHEMBL22563313 | 0.85 | CTRB1 (0.62) | FCER2MMP1CTRB1 | |
| SCHEMBL7446381 | 0.81 | MME (0.57) | — | |
| SCHEMBL7437631 | 0.81 | MME (0.57) | — | |
| SCHEMBL29655902 | 0.80 | CTRB1 (0.57) | FCER2MMP1CTRB1 | |
| SCHEMBL11220056 | 0.79 | RAB9A (0.51) | CTSCRAB9A | |
| SCHEMBL29702065 | 0.79 | MME (0.61) | CTRB1 | |
| SCHEMBL26254919 | 0.79 | NPY4R (0.50) | CTSCCTSL | |
| SCHEMBL12464485 | 0.77 | CTSC (0.47) | CTSC | |
| SCHEMBL31462418 | 0.77 | MME (0.60) | CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |