Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431161 | 0.95 | RAB9A (0.39) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7431007 | 0.94 | ITGB3 (0.41) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7386959 | 0.94 | RAB9A (0.42) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7394349 | 0.93 | RAB9A (0.44) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7391203 | 0.93 | ITGB3 (0.41) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7387851 | 0.92 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7388128 | 0.92 | ITGB3 (0.40) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7434120 | 0.91 | DRD3 (0.41) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7432983 | 0.91 | NPC1 (0.41) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT | |
| SCHEMBL7394654 | 0.89 | RAB9A (0.46) | ITGB3ITGA2BSMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |