Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 6/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421110 | 0.88 | MLLT1 (0.38) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7446447 | 0.85 | F2 (0.40) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7450500 | 0.85 | MLLT1 (0.39) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7447512 | 0.83 | MLLT1 (0.37) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7414753 | 0.81 | F2 (0.49) | NPC1RAB9AF2F10 | |
| SCHEMBL7422210 | 0.80 | F2 (0.40) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL7447141 | 0.77 | MLLT1 (0.37) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7442317 | 0.73 | F2 (0.54) | MLLT1MAPTNPC1ALDH1A1LMNA | |
| SCHEMBL7449396 | 0.71 | MAPT (0.37) | MLLT1P2RY12MAPTNPC1ALDH1A1 | |
| SCHEMBL7453719 | 0.71 | F2 (0.42) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |