Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 2/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450500 | 0.86 | MLLT1 (0.39) | MLLT1F2F10CASRNPC1 | |
| SCHEMBL7446447 | 0.86 | F2 (0.40) | MLLT1F2F10CASRNPC1 | |
| SCHEMBL7447512 | 0.81 | MLLT1 (0.37) | MLLT1F2F10CASRNPC1 | |
| SCHEMBL7421110 | 0.79 | MLLT1 (0.38) | MLLT1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL7445649 | 0.77 | MLLT1 (0.37) | MLLT1F2F10NPC1ALDH1A1 | |
| SCHEMBL7442317 | 0.74 | F2 (0.54) | MLLT1F2F10NPC1ALDH1A1 | |
| SCHEMBL7450241 | 0.73 | F2 (0.57) | MLLT1F2F10 | |
| SCHEMBL7454804 | 0.72 | F2 (0.44) | F2F10RAB9A | |
| SCHEMBL7449708 | 0.70 | MLLT1 (0.42) | MLLT1DPP7 | |
| SCHEMBL7415304 | 0.67 | F2 (0.59) | F2F10NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |