Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735887 | 0.83 | KMT2A (0.43) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3659518 | 0.81 | PEPD (0.54) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL12378828 | 0.81 | MEN1 (0.52) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3995569 | 0.81 | ESR1 (0.55) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL161755 | 0.81 | MEN1 (0.52) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11647073 | 0.81 | CA1 (0.41) | CA12CA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27072143 | 0.80 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2OGG1HDAC1 | |
| SCHEMBL5518500 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL4395547 | 0.79 | NPC1 (0.55) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL28470399 | 0.79 | KMT2A (0.55) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | claimed |